ruthenium red मीनिंग इन हिंदी

Pepper spray antidotes exist; examples include capsazepine, ruthenium red, and other TRPV1 antagonists.
Ruthenium red and Ru360 are typical reagents used to experimentally block the MCU to study its properties and role in mitochondrial signaling.
Ru360 was discovered after scientists found that commercial preparations of ruthenium red were often less than 20 % pure, and that the crude mixture produced a stronger inhibition than the purified product.
Ruthenium red, [ ( NH 3 ) 5 Ru-O-Ru ( NH 3 ) 4-O-Ru ( NH 3 ) 5 ] 6 +, is a biological stain used to stain polyanionic molecules such as pectin and nucleic acids for light microscopy and electron microscopy.
The discovery of unselective modulators ( e . g . antagonist Ruthenium Red ) was followed by the apparition of more potent ( agonist 4aPDD ) or selective ( antagonist RN-1734 ) compounds, including some with bioavailability suitable for in vivo pharmacology studies such as agonist GSK1016790A ( with ~ 10 fold selectivity vs TRPV1 ), and antagonists HC-067047 ( with ~ 5 fold selectivity vs hERG and ~ 10 fold selectivity vs TRPM8 ) and RN-9893 ( with ~ 50 fold selectivity vs TRPM8 and ~ 10 fold selectivity vs M1 ).